A proteome is a full complement of a protein produced a specific cell, tissue, genome or an organism. In particular terms, a proteome is a set of articulated proteins within specific conditions and at a given time. Proteome is a portmanteau word of genome and proteins. Proteome term is functional in more than a few biological systems. For instance, cellular proteome is a set of proteins of a particular cell under defined surroundings such as the possible exposure to hormone stimulation. An organism’s entire proteome can be conceived to be a complete set of all cellular proteome. This set of proteomes is almost protein equal of a genome. Proteome is also used to refer protein aggregation in particular sub-cellular biological structures. For instance, collective proteins in a virus are termed as viral proteome. Proteome is structurally larger than a genome particularly in organisms with membrane bound nuclei in the context that they have more genes and protein due to the post-translational modifications and alternative splicing of genes.
Proteomics term papers mainly tend to focus upon detailed descriptions of separation of proteins by means of gel electrophoresis. In term papers pertaining to two dimensional gel electrophoresis students are given the task of giving detailed descriptions of the methods. For instance, students are asked to give detailed explanations of isoelectric focusing and SDS-PAGE. In research papers, students are given the opportunity to describe the possible results of using these methods as well as more complicated and advanced ones such as peptide mass fingerprinting. |